Design Optimization of Blood Diagnosis Chips using Computational Techniques

Abstract

The conventional blood testing methods are either expensive or require a large detection time. Whereas other methods based on bio- chip principle have laminar flow in them which reduces the probability of detection of disease. Moreover methods used nowadays for the blood diagnosis require a lot of equipment and so these tests become uneconomical and cumbersome. Therefore an idea is to design and develop portable and inexpensive equipment for the blood diagnosis for the detection of diseases in a short time. The purpose here is to increase the probability of detection of disease. Therefore, few models are analysed to obtain the optimum design for the diagnosis of blood using CFD technique. By creating certain obstructions in the flow, we will try to have effective utilisation of area of the rectangular trench so that fluid will flow over all the area increasing the probability of detection. Obstructions in the flow of the fluid in the rectangular trench are cylindrical hole, square hole, inclined baffles, straight baffles and straight baffles with square hole. The obstruction of the straight baffles having 90° angle and without gap gives good results. The velocity is minimum for the straight baffle model and to have proper reaction the velocity should be minimum.